Single nucleotide polymorphisms at miR-146a/196a2 and their primary ovarian insufficiency-related target gene regulation in granulosa cells.

Single nucleotide polymorphisms at miR-146a/196a2 and their primary ovarian insufficiency-related target gene regulation in granulosa cells.

MicroRNAs post-transcriptionally regulate gene expression in animals and plants. The aim of this study was to identify new target genes for microRNA polymorphisms (miR-146aC>G and miR-196a2T>C) in primary ovarian insufficiency (POI). We cloned and transfected miR-146aC>G and miR-196a2T>C...

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Bibliographic Details
Main Authors: Sung Hwan Cho, Hui Jeong An, Kyung Ah Kim, Jung Jae Ko, Ji Hyang Kim, Young Ran Kim, Eun Hee Ahn, HyungChul Rah, Woo Sik Lee, Nam Keun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5571913?pdf=render

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http://europepmc.org/articles/PMC5571913?pdf=render

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