Manganese-enhanced MRI reveals changes within brain anxiety and aversion circuitry in rats with chronic neuropathic pain- and anxiety-like behaviors

Manganese-enhanced MRI reveals changes within brain anxiety and aversion circuitry in rats with chronic neuropathic pain- and anxiety-like behaviors

Chronic pain often predicts the onset of psychological distress. Symptoms including anxiety and depression after pain chronification reportedly are caused by brain remodeling/recruitment of the limbic and reward/aversion circuitries. Pain is the primary precipitating factor that has caused opioid ov...

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Bibliographic Details
Main Authors: Sabrina L. McIlwrath, Marena A. Montera, Katherine M. Gott, Yirong Yang, Colin M. Wilson, Reed Selwyn, Karin N. Westlund
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:NeuroImage
Subjects:
Magnetic resonance imaging
Neuropathic pain
Chronic pain
Trigeminal nerve
Orofacial pain
CCI-ION
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811920308296

Internet

http://www.sciencedirect.com/science/article/pii/S1053811920308296

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