KCHO-1, a Novel Antineuroinflammatory Agent, Inhibits Lipopolysaccharide-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglia Cells

KCHO-1, a Novel Antineuroinflammatory Agent, Inhibits Lipopolysaccharide-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglia Cells

The brain is vulnerable to oxidative stress and inflammation that can occur as a result of aging or neurodegenerative diseases. Our work has sought to identify natural products that regulate heme oxygenase (HO)-1 and to determine their mechanism of action in neurodegenerative diseases. KCHO-1 is a n...

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Bibliographic Details
Main Authors: Dong-Sung Lee, Wonmin Ko, Chi-Su Yoon, Dong-Cheol Kim, Jinju Yun, Jun-Kyung Lee, Ki-Young Jun, Ilhong Son, Dong-Woung Kim, Bong-Keun Song, Seulah Choi, Jun-Hyeog Jang, Hyuncheol Oh, Sungchul Kim, Youn-Chul Kim
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2014/357154

Internet

http://dx.doi.org/10.1155/2014/357154

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