Use of a recombinant <it>Salmonella enterica </it>serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice

<p>Abstract</p> <p>Background</p> <p>Serine-threonine kinases of the Raf family (A-Raf, B-Raf, C-Raf) are central players in cellular signal transduction, and thus often causally involved in the development of cancer when mutated or over-expressed. Therefore these prote...

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Bibliographic Details
Main Authors: Troppmair Jakob, Potapenko Tamara, Schmidt Andreas, Fensterle Joachim, Gentschev Ivaylo, Goebel Werner, Rapp Ulf R
Format: Article
Language:English
Published: BMC 2005-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/15