Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs.

Four full-sibling intact male Miniature Poodles were evaluated at 4-19 months of age. One was clinically normal and three were affected. All affected dogs were reluctant to exercise and had generalised muscle atrophy, a stiff gait and a markedly elevated serum creatine kinase activity. Two affected...

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Bibliographic Details
Main Authors: Lluís Sánchez, Elsa Beltrán, Alberta de Stefani, Ling T Guo, Anita Shea, G Diane Shelton, Luisa De Risio, Louise M Burmeister
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5825102?pdf=render