Determinants of Plasma Docosahexaenoic Acid Levels and Their Relationship to Neurological and Cognitive Functions in PKU Patients: A Double Blind Randomized Supplementation Study

Children with phenylketonuria (PKU) follow a protein restricted diet with negligible amounts of docosahexaenoic acid (DHA). Low DHA intakes might explain subtle neurological deficits in PKU. We studied whether a DHA supply modified plasma DHA and neurological and intellectual functioning in PKU. In...

Full description

Bibliographic Details
Main Authors: Hans Demmelmair, Anita MacDonald, Urania Kotzaeridou, Peter Burgard, Domingo Gonzalez-Lamuno, Elvira Verduci, Melike Ersoy, Gulden Gokcay, Behiye Alyanak, Eva Reischl, Wolfgang Müller-Felber, Fabienne Lara Faber, Uschi Handel, Sabrina Paci, Berthold Koletzko
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/10/12/1944