Hydrogen sulfide stimulates xanthine oxidoreductase conversion to nitrite reductase and formation of NO

Cardiovascular disease is the leading cause of death and disability worldwide with increased oxidative stress and reduced NO bioavailability serving as key risk factors. For decades, elevation in protein abundance and enzymatic activity of xanthine oxidoreductase (XOR) under hypoxic/inflammatory con...

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Bibliographic Details
Main Authors: Sibile Pardue, Gopi K. Kolluru, Xinggui Shen, Sara E. Lewis, Courtney B. Saffle, Eric E. Kelley, Christopher G. Kevil
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719315885