2′-Fucosyllactose impacts the expression of mucus-related genes in goblet cells and maintains barrier function of gut epithelial cells

2′-Fucosyllactose impacts the expression of mucus-related genes in goblet cells and maintains barrier function of gut epithelial cells

Scope: Cost-effective microbial biosynthesis of 2′-fucosyllactose (2′-FL) allows its application in infant formula. The specific effects of 2′-FL on the gastrointestinal immune barrier are still largely unknown. Methods/results: Here, we quantified and compared the effects of HMOs isolated from huma...

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Bibliographic Details
Main Authors: Susana Figueroa-Lozano, Renate Akkerman, Martin Beukema, Sander S. van Leeuwen, Lubbert Dijkhuizen, Paul de Vos
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Functional Foods
Subjects:
Human milk oligosaccharides (HMOs)
2′-fucosyllactose
Goblet cells
TEER
Barrier function
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621002796

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http://www.sciencedirect.com/science/article/pii/S1756464621002796

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