Large‐scale survey and database of high affinity ligands for peptide recognition modules

Large‐scale survey and database of high affinity ligands for peptide recognition modules

Abstract Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction partners. Here, we used large‐scale peptide‐phage display methods to derive optimal ligands for 163 unique PRMs representing 79 distin...

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Bibliographic Details
Main Authors: Joan Teyra, Abdellali Kelil, Shobhit Jain, Mohamed Helmy, Raghav Jajodia, Yogesh Hooda, Jun Gu, Akshay A D’Cruz, Sandra E Nicholson, Jinrong Min, Marius Sudol, Philip M Kim, Gary D Bader, Sachdev S Sidhu
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Molecular Systems Biology
Subjects:
domain specificity
peptide inhibitors
peptide library
peptide recognition modules
phage display
Online Access:https://doi.org/10.15252/msb.20199310

Internet

https://doi.org/10.15252/msb.20199310

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