A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice[S]

A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice[S]

Intracellular lipids and their synthesis contribute to the mechanisms and complications of obesity-associated diseases. We describe an NMR approach that provides an abbreviated lipidomic analysis with concurrent lipid biosynthetic fluxes. Following deuterated water administration, positional isotopo...

Full description

Bibliographic Details
Main Authors: Joao A.G. Duarte, Filipa Carvalho, Mackenzie Pearson, Jay D. Horton, Jeffrey D. Browning, John G. Jones, Shawn C. Burgess
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Journal of Lipid Research
Subjects:
lipid metabolism
obesity
liver
adipose
nuclear magnetic resonance
lipidomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520366943

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520366943

Similar Items