Snail promotes epithelial mesenchymal transition in breast cancer cells in part via activation of nuclear ERK2.

Snail promotes epithelial mesenchymal transition in breast cancer cells in part via activation of nuclear ERK2.

Snail transcription factor is up-regulated in several cancers and associated with increased tumor migration and invasion via induction of epithelial-to-mesenchymal transition (EMT). MAPK (ERK1/2) signaling regulates cellular processes including cell motility, adhesion, and invasion. We investigated...

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Bibliographic Details
Main Authors: Bethany N Smith, Liza J Burton, Veronica Henderson, Diandra D Randle, Derrick J Morton, Basil A Smith, Latonia Taliaferro-Smith, Peri Nagappan, Clayton Yates, Majd Zayzafoon, Leland W K Chung, Valerie A Odero-Marah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4133359?pdf=render

Internet

http://europepmc.org/articles/PMC4133359?pdf=render

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