Snail promotes epithelial mesenchymal transition in breast cancer cells in part via activation of nuclear ERK2.
Snail transcription factor is up-regulated in several cancers and associated with increased tumor migration and invasion via induction of epithelial-to-mesenchymal transition (EMT). MAPK (ERK1/2) signaling regulates cellular processes including cell motility, adhesion, and invasion. We investigated...
Main Authors: | Bethany N Smith, Liza J Burton, Veronica Henderson, Diandra D Randle, Derrick J Morton, Basil A Smith, Latonia Taliaferro-Smith, Peri Nagappan, Clayton Yates, Majd Zayzafoon, Leland W K Chung, Valerie A Odero-Marah |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4133359?pdf=render |
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