MK2-dependent p38b signalling protects Drosophila hindgut enterocytes against JNK-induced apoptosis under chronic stress.

The integrity of the intestinal epithelium is crucial for the barrier function of the gut. Replenishment of the gut epithelium by intestinal stem cells contributes to gut homeostasis, but how the differentiated enterocytes are protected against stressors is less well understood. Here we use the Dros...

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Bibliographic Details
Main Authors: Gerhard Seisenbacher, Ernst Hafen, Hugo Stocker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3150449?pdf=render