The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation

The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation

The ADAMTS5 metzincin, a secreted zinc-dependent metalloproteinase, modulates the extracellular matrix (ECM) during limb morphogenesis and other developmental processes. Here, the role of ADAMTS5 was investigated by knockdown of zebrafish adamts5 during embryogenesis. This revealed impaired Sonic He...

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Bibliographic Details
Main Authors: Carolyn M. Dancevic, Yann Gibert, Joachim Berger, Adam D. Smith, Clifford Liongue, Nicole Stupka, Alister C. Ward, Daniel R. McCulloch
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
metalloproteinase
extracellular matrix
ADAMTS
somite
muscle
zebrafish
Online Access:http://www.mdpi.com/1422-0067/19/3/766

Internet

http://www.mdpi.com/1422-0067/19/3/766

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