A non-viral genome editing platform for site-specific insertion of large transgenes
Abstract Background The precise, functional and safe insertion of large DNA payloads into host genomes offers versatility in downstream genetic engineering-associated applications, spanning cell and gene therapies, therapeutic protein production, high-throughput cell-based drug screening and reporte...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-09-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13287-020-01890-6 |