RUTI Vaccination Enhances Inhibition of Mycobacterial Growth ex vivo and Induces a Shift of Monocyte Phenotype in Mice

RUTI Vaccination Enhances Inhibition of Mycobacterial Growth ex vivo and Induces a Shift of Monocyte Phenotype in Mice

Tuberculosis (TB) is a major global health problem and there is a dire need for an improved treatment. A strategy to combine vaccination with drug treatment, termed therapeutic vaccination, is expected to provide benefit in shortening treatment duration and augmenting treatment success rate. RUTI ca...

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Bibliographic Details
Main Authors: Satria A. Prabowo, Hannah Painter, Andrea Zelmer, Steven G. Smith, Karin Seifert, Merce Amat, Pere-Joan Cardona, Helen A. Fletcher
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
RUTI
vaccine
tuberculosis
monocytes
mycobacteria
growth inhibition assay
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00894/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00894/full

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