Polyphenol-rich ethyl acetate fraction of Molineria latifolia rhizome restores oxidant-antioxidant balance by possible engagement of KEAP1-NRF2 and PKC/NF-κB signalling pathways

Polyphenol-rich ethyl acetate fraction of Molineria latifolia rhizome restores oxidant-antioxidant balance by possible engagement of KEAP1-NRF2 and PKC/NF-κB signalling pathways

The present study examined the potential of ethyl acetate fraction (EAF) isolated from Molineria latifolia rhizome to modulate the oxidant-antioxidant balance in high fat diet and nicotinamide/streptozotocin-induced diabetic rats. Administration with EAF ameliorated systemic antioxidant status- and...

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Bibliographic Details
Main Authors: Der Jiun Ooi, Kim Wei Chan, Norsharina Ismail, Mustapha Umar Imam, Maznah Ismail
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Functional Foods
Subjects:
Ethyl acetate fraction
Oxidant-antioxidant balance
Diabetes mellitus
KEAP1-NRF2 signalling
PKC/NF-κB signalling
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617307168

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http://www.sciencedirect.com/science/article/pii/S1756464617307168

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