Functional loss of Ccdc151 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia

Functional loss of Ccdc151 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder affecting normal structure and function of motile cilia, phenotypically manifested as chronic respiratory infections, laterality defects and infertility. Autosomal recessive mutations in genes encoding for different components...

Full description

Bibliographic Details
Main Authors: Francesco Chiani, Tiziana Orsini, Alessia Gambadoro, Miriam Pasquini, Sabrina Putti, Maurizio Cirilli, Olga Ermakova, Glauco P. Tocchini-Valentini
Format: Article
Language:English
Published: The Company of Biologists 2019-08-01
Series:Disease Models & Mechanisms
Subjects:
Gene knockout
X-ray gene expression imaging
MicroCT brain imaging
CSF
Cilia
IMPC
Online Access:http://dmm.biologists.org/content/12/8/dmm038489

Internet

http://dmm.biologists.org/content/12/8/dmm038489

Similar Items