Peak expiratory flow as an endpoint for clinical trials in asthma: a comparison with FEV1

Peak expiratory flow as an endpoint for clinical trials in asthma: a comparison with FEV1

Abstract Background The primary lung function endpoint in clinical trials in adolescent and adult patients with asthma is usually forced expiratory volume in one second (FEV1). The objective of our analysis was to assess whether peak expiratory flow (PEF) is a suitable alternative primary lung funct...

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Bibliographic Details
Main Authors: David M. G. Halpin, Eli O. Meltzer, Wendelgard Pisternick-Ruf, Petra Moroni-Zentgraf, Michael Engel, Liliana Zaremba-Pechmann, Thomas Casale, J. Mark FitzGerald
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Respiratory Research
Subjects:
Asthma
Correlation
FEV1
Home-measurement
In-clinic measurement
PEF
Online Access:http://link.springer.com/article/10.1186/s12931-019-1119-6

Internet

http://link.springer.com/article/10.1186/s12931-019-1119-6

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