Anomalies in network bridges involved in bile Acid metabolism predict outcomes of colorectal cancer patients.

Biomarkers prognostic for colorectal cancer (CRC) would be highly desirable in clinical practice. Proteins that regulate bile acid (BA) homeostasis, by linking metabolic sensors and metabolic enzymes, also called bridge proteins, may be reliable prognostic biomarkers for CRC. Based on a devised metr...

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Bibliographic Details
Main Authors: Sunjae Lee, KiYoung Lee, Seyeol Yoon, Jae W Lee, Doheon Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107925