Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis

Inducing sterile pyramidal neuronal death in mice to model distinct aspects of gray matter encephalitis

Abstract Up to one person in a population of 10,000 is diagnosed once in lifetime with an encephalitis, in 50–70% of unknown origin. Recognized causes amount to 20–50% viral infections. Approximately one third of affected subjects develops moderate and severe subsequent damage. Several neurotropic v...

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Bibliographic Details
Main Authors: Justus B. H. Wilke, Martin Hindermann, Amir Moussavi, Umer Javed Butt, Rakshit Dadarwal, Stefan A. Berghoff, Aref Kalantari Sarcheshmeh, Anja Ronnenberg, Svenja Zihsler, Sahab Arinrad, Rüdiger Hardeland, Jan Seidel, Fred Lühder, Klaus-Armin Nave, Susann Boretius, Hannelore Ehrenreich
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Acta Neuropathologica Communications
Subjects:
Diphtheria toxin
Hippocampal learning and memory
(pre)frontal network dysfunction
Social cognition
Thermography
Magnetic resonance imaging
Online Access:https://doi.org/10.1186/s40478-021-01214-6

Internet

https://doi.org/10.1186/s40478-021-01214-6

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