Mass Generation, Neuron Labeling, and 3D Imaging of Minibrains

Minibrain is a 3D brain in vitro spheroid model, composed of a mixed population of neurons and glial cells, generated from human iPSC derived neural stem cells. Despite the advances in human 3D in vitro models such as aggregates, spheroids and organoids, there is a lack of labeling and imaging metho...

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Bibliographic Details
Main Authors: Subashika Govindan, Laura Batti, Samira F. Osterop, Luc Stoppini, Adrien Roux
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.582650/full