Upcoming pharmacological developments in chronic hepatitis B: can we glimpse a cure on the horizon?

Abstract Background Hepatitis B virus (HBV) chronic infection affects up to 240 million people in the world and it is a common cause of cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) plays an essential role in HBV persistence and replication. Current pharma...

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Bibliographic Details
Main Authors: Sonia Alonso, Adriana-René Guerra, Lourdes Carreira, Juan-Ángel Ferrer, María-Luisa Gutiérrez, Conrado M. Fernandez-Rodriguez
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Gastroenterology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12876-017-0726-2