Assessing age-related grey matter decline with Voxel-Based Morphometry depends significantly on segmentation and normalisation procedures

Assessing age-related grey matter decline with Voxel-Based Morphometry depends significantly on segmentation and normalisation procedures

Healthy ageing coincides with a progressive decline of brain grey matter (GM) ultimately affecting the entire brain. For a long time, manual delineation-based volumetry within predefined regions of interest (ROI) has been the gold standard for assessing such degeneration. Voxel-Based Morphometry (V...

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Bibliographic Details
Main Authors: Dorothée V Callaert, Annemie eRibbens, Frederik eMaes, Stephan Patrick Swinnen, Nicole eWenderoth
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Atrophy
Brain Mapping
Ageing
MRI
segmentation
Grey Matter
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00124/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00124/full

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