Shared and Distinct Phenotypes and Functions of Human CD161++ Vα7.2+ T Cell Subsets

Shared and Distinct Phenotypes and Functions of Human CD161++ Vα7.2+ T Cell Subsets

Human mucosal-associated invariant T (MAIT) cells are an important T cell subset that are enriched in tissues and possess potent effector functions. Typically such cells are marked by their expression of Vα7.2-Jα33/Jα20/Jα12 T cell receptors, and functionally they are major histocompatibility comple...

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Bibliographic Details
Main Authors: Ayako Kurioka, Aminu S. Jahun, Rachel F. Hannaway, Lucy J. Walker, Joannah R. Fergusson, Eva Sverremark-Ekström, Alexandra J. Corbett, James E. Ussher, Christian B. Willberg, Paul Klenerman
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
mucosal-associated invariant T cells
innate-like T cells
MHC class I-related protein 1-tetramer
MHC class I-related protein 1
subsets
transcription factors
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01031/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.01031/full

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