Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions

Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions

Telomeres define the natural ends of eukaryotic chromosomes and are crucial for chromosomal stability. The budding yeast Cdc13, Stn1 and Ten1 proteins form a heterotrimeric complex, and the inactivation of any of its subunits leads to a uniformly lethal phenotype due to telomere deprotection. Althou...

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Bibliographic Details
Main Authors: Zhi-Jing Wu, Jia-Cheng Liu, Xin Man, Xin Gu, Ting-Yi Li, Chen Cai, Ming-Hong He, Yangyang Shao, Ning Lu, Xiaoli Xue, Zhongjun Qin, Jin-Qiu Zhou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
single chromosome yeast
CST complex
chromosome end fusion
telomere protection
homologous recombination
Online Access:https://elifesciences.org/articles/53144

Internet

https://elifesciences.org/articles/53144

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