The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development.

The aryl hydrocarbon receptor (AhR) has been shown to be required for optimal Thelper (Th) 17 cell activation. Th17 cells provide immunity against extracellular pathogens and are implicated in autoimmune diseases. Herein, the role of the AhR in cytokine production by Th17, and by the analogous popul...

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Bibliographic Details
Main Authors: Mark D Hayes, Vitalijs Ovcinnikovs, Andrew G Smith, Ian Kimber, Rebecca J Dearman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4159274?pdf=render