A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin.

Responsiveness of cells to alpha-toxin (Hla) from Staphylococcus aureus appears to occur in a cell-type dependent manner. Here, we compare two human bronchial epithelial cell lines, i.e. Hla-susceptible 16HBE14o- and Hla-resistant S9 cells, by a quantitative multi-omics strategy for a better underst...

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Bibliographic Details
Main Authors: Erik Richter, Manuela Harms, Katharina Ventz, Philipp Gierok, Ravi Kumar Chilukoti, Jan-Peter Hildebrandt, Jörg Mostertz, Falko Hochgräfe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376684?pdf=render