A refractory case of CDK4-amplified spinal astrocytoma achieving complete response upon treatment with a Palbociclib-based regimen:a case report

A refractory case of CDK4-amplified spinal astrocytoma achieving complete response upon treatment with a Palbociclib-based regimen:a case report

Abstract Background Spinal cord astrocytoma is a rare neoplasm, and patients usually recur within months after surgery. There is currently a lack of consensus regarding post-operative treatment. Clinical data on the activity of systemic treatment like chemoradiotherapy and anti-angiogenic agents als...

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Bibliographic Details
Main Authors: Jietao Lin, Ling Yu, Yuanfeng Fu, Hanrui Chen, Xinting Zheng, Shutang Wang, Chan Gao, Yang Cao, Lizhu Lin
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Cancer
Subjects:
Spinal astrocytoma
next-generation sequencing
Palbociclib
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s12885-020-07061-3

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http://link.springer.com/article/10.1186/s12885-020-07061-3

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