Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195

Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195

Abstract Background Metabolic memory contributes to the development of diabetic retinopathy (DR), which is the complication of diabetes. But it’s still unknown how to prevent the metabolic memory to treat the DR. In our study, we want to examine the function of Astragalus polysaccharides (APS) in th...

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Bibliographic Details
Main Authors: Ping Liu, Qing-Hua Peng, Ping Tong, Wen-Jie Li
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Medicine
Subjects:
Metabolic memory
Diabetic retinopathy
Mitochondrial damage
Apoptosis
Astragalus polysaccharides
miR-195
Online Access:http://link.springer.com/article/10.1186/s10020-019-0088-z

Internet

http://link.springer.com/article/10.1186/s10020-019-0088-z

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