Novel single-domain antibodies against the EGFR domain III epitope exhibit the anti-tumor effect

Abstract Background Monoclonal antibodies (mAbs) have been used for cancer therapy. They are large and have some disadvantages limiting their use. Smaller antibody fragments are needed as their alternatives. A fully human single-domain antibody (sdAb) has a small size of only 15 kDa and consists of...

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Bibliographic Details
Main Authors: Tao Chen, Xue Liu, Haifeng Hong, Henry Wei
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-020-02538-y