GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation

<p>Abstract</p> <p>Background</p> <p>After liver injury, the repair process comprises activation and proliferation of hepatic stellate cells (HSCs), which produce extracellular matrix (ECM) proteins. Peroxisome proliferator-activated receptor beta/delta <b>(</b...

Full description

Bibliographic Details
Main Authors: Kostadinova Radina, Montagner Alexandra, Gouranton Erwan, Fleury Sébastien, Guillou Hervé, Dombrowicz David, Desreumaux Pierre, Wahli Walter
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Cell & Bioscience
Subjects:
Peroxisome proliferator-activated receptor β/δ
Inflammation
Fibrosis
Signaling pathways
Proliferation
Online Access:http://www.cellandbioscience.com/content/2/1/34

Internet

http://www.cellandbioscience.com/content/2/1/34

Similar Items