Programming of Dopaminergic Neurons by Early Exposure to Sex Hormones: Effects on Morphine-Induced Accumbens Dopamine Release, Reward, and Locomotor Behavior in Male and Female Rats

Programming of Dopaminergic Neurons by Early Exposure to Sex Hormones: Effects on Morphine-Induced Accumbens Dopamine Release, Reward, and Locomotor Behavior in Male and Female Rats

Neonatal programming with sex hormones produces long-term functional changes in various tissues, including the brain. Previously, we demonstrated a higher content of dopamine and an increase in potassium-induced dopamine release in the nucleus accumbens of adult rats exposed to estradiol valerate. O...

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Bibliographic Details
Main Authors: Victoria B. Velásquez, Gabriel A. Zamorano, Jonathan Martínez-Pinto, Christian Bonansco, Pablo Jara, Gonzalo E. Torres, Georgina M. Renard, Ramón Sotomayor-Zárate
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
dopamine
morphine
microdialysis
estradiol
testosterone
programming
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00295/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00295/full

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