Novel method of real-time PCR-based screening for common fetal trisomies

Novel method of real-time PCR-based screening for common fetal trisomies

Abstract Background The non-invasive prenatal test (NIPT) is based on next generation sequencing (NGS) and is used for screening for fetal trisomy. However, it is time-consuming and technically difficult. Recently, peptide nucleic acid (PNA) probe-based real-time polymerase chain reaction (RT-PCR) w...

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Bibliographic Details
Main Authors: So Yeon Kim, Seung Mi Lee, Sun Min Kim, Byoung Jae Kim, Ja Nam Koo, Ig Hwan Oh, Sohee Oh, Chan-Wook Park, Jong Kwan Jun, Ji Hyae Lim, Hyun Mee Ryu, Joong Shin Park
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Medical Genomics
Subjects:
Fetal trisomy
Prenatal diagnosis
Non-invasive prenatal test
Real-time polymerase chain reaction
Peptide nucleic acid
Online Access:https://doi.org/10.1186/s12920-021-01039-1

Internet

https://doi.org/10.1186/s12920-021-01039-1

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