Ripples Have Distinct Spectral Properties and Phase-Amplitude Coupling With Slow Waves, but Indistinct Unit Firing, in Human Epileptogenic Hippocampus

Ripples Have Distinct Spectral Properties and Phase-Amplitude Coupling With Slow Waves, but Indistinct Unit Firing, in Human Epileptogenic Hippocampus

Ripple oscillations (80–200 Hz) in the normal hippocampus are involved in memory consolidation during rest and sleep. In the epileptic brain, increased ripple and fast ripple (200–600 Hz) rates serve as a biomarker of epileptogenic brain. We report that both ripples and fast ripples exhibit a prefer...

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Bibliographic Details
Main Authors: Shennan A. Weiss, Inkyung Song, Mei Leng, Tomás Pastore, Diego Slezak, Zachary Waldman, Iren Orosz, Richard Gorniak, Mustafa Donmez, Ashwini Sharan, Chengyuan Wu, Itzhak Fried, Michael R. Sperling, Anatol Bragin, Jerome Engel, Yuval Nir, Richard Staba
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neurology
Subjects:
sleep
high-frequency oscillation
slow wave
epilepsy
hippocampus
ripple
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00174/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00174/full

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