Transcriptome-based analysis of blood samples reveals elevation of DNA damage response, neutrophil degranulation, cancer and neurodegenerative pathways in Plasmodium falciparum patients

Transcriptome-based analysis of blood samples reveals elevation of DNA damage response, neutrophil degranulation, cancer and neurodegenerative pathways in Plasmodium falciparum patients

Abstract Background Malaria caused by Plasmodium falciparum results in severe complications including cerebral malaria (CM) especially in children. While the majority of falciparum malaria survivors make a full recovery, there are reports of some patients ending up with neurological sequelae or cogn...

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Bibliographic Details
Main Authors: Akua A. Karikari, Wasco Wruck, James Adjaye
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Malaria Journal
Subjects:
Cerebral malaria
P. falciparum
Cellular stress
Immune response
Neutrophil degranulation
Axonal dysfunction
Online Access:https://doi.org/10.1186/s12936-021-03918-5

Internet

https://doi.org/10.1186/s12936-021-03918-5

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