1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents

A series of 1,2-, 1,4-disubstituted or 1,2,4-trisubstituted anthraquinone-based compounds was designed, synthesized, characterized and biologically evaluated for anticancer efficacy. 2- or 4-arylated 1-hydroxy-9,10-antraquinones (anthracene-9,10-diones) were prepared by Suzuki–Miyaura cross-coupling...

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Bibliographic Details
Main Authors: Nafisa S. Sirazhetdinova, Victor A. Savelyev, Tatyana S. Frolova, Dmitry S. Baev, Lyubov S. Klimenko, Ivan V. Chernikov, Olga S. Oleshko, Teresa A. Sarojan, Andrey G. Pokrovskii, Elvira E. Shults
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/11/2547