Differential genetic mutations of ectoderm, mesoderm, and endoderm-derived tumors in TCGA database

Abstract Background In terms of biological behavior, gene regulation, or signaling pathways, there is a certain similarity between tumorigenesis and embryonic development of humans. Three germ layer structure exhibits the distinct ability to form specific tissues and organs. Methods The present stud...

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Bibliographic Details
Main Authors: Xingjie Gao, Xiaoteng Cui, Xinxin Zhang, Chunyan Zhao, Nan Zhang, Yan Zhao, Yuanyuan Ren, Chao Su, Lin Ge, Shaoyuan Wu, Jie Yang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-020-01678-x