In vitro anti-mycobacterial activity of (E)-N´-(monosubstituted-benzylidene) isonicotinohydrazide derivatives against isoniazid-resistant strains

In vitro anti-mycobacterial activity of (E)-N´-(monosubstituted-benzylidene) isonicotinohydrazide derivatives against isoniazid-resistant strains

A series of twenty-three <em>N-acylhydrazones</em> derived from isoniazid (INH 1-23) have been evaluated for their <em>in vitro</em> antibacterial activity against INH- susceptible strain of <em>M. tuberculosis</em> (RG500) and three INH-resistant clinical isolate...

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Bibliographic Details
Main Authors: Tatiane S. Coelho, Jessica B. Cantos, Marcelle L.F. Bispo, Raoni S.B. Gonçalves, Camilo H.S. Lima, Pedro E.A. da Silva, Marcus De Souza
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Infectious Disease Reports
Subjects:
tuberculosis, isoniazid, INH-resistance, N-acylhydrazones, drugs
Online Access:http://www.pagepress.org/journals/index.php/idr/article/view/3189

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http://www.pagepress.org/journals/index.php/idr/article/view/3189

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