Syngeneic leukemia models using lentiviral transgenics

Abstract Animal models are necessary to study cancer and develop treatments. After decades of intensive research, effective treatments are available for only a few types of leukemia, while others are currently incurable. Our goal was to generate novel leukemia models in immunocompetent mice. We had...

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Bibliographic Details
Main Authors: Nurit Keinan, Ye’ela Scharff, Oron Goldstein, Michael Chamo, Stefan Ilic, Roi Gazit
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03477-2