Association of p62/SQSTM1 excess and oral carcinogenesis.

p62/SQSTM1 (sequestosome1) has never been evaluated in oral epithelium. In order to clarify the role of p62/SQSTM1 in carcinogenesis in oral epithelium, both p62/SQSTM1 and Nrf2 were immunohistochemically evaluated in 54 carcinomas and 14 low grade dysplasias. p62/SQSTM1 knockdowns were also designe...

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Bibliographic Details
Main Authors: Takuma Inui, Tokuhiro Chano, Mikiko Takikita-Suzuki, Masanori Nishikawa, Gaku Yamamoto, Hidetoshi Okabe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3782476?pdf=render