Copy number-based quantification assay for non-invasive detection of PVT1-derived transcripts.

BACKGROUND:One of the most important susceptibility loci for cancer is the 8q24 human chromosomal region. The non-protein coding gene locus plasmacytoma variant translocation 1 (PVT1) is located at 8q24 and is dysregulated in prostate cancer. PVT1 gives rise to multiple transcripts which may have di...

Full description

Bibliographic Details
Main Authors: Gargi Pal, Olorunseun O Ogunwobi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226620