Tepary Bean (<i>Phaseolus acutifolius</i>) Lectins Induce Apoptosis and Cell Arrest in G0/G1 by P53(Ser46) Phosphorylation in Colon Cancer Cells

A Tepary bean lectin fraction (TBLF) has been studied because it exhibits differential cytotoxic and anticancer effects on colon cancer. The present work focuses on the evaluation of the apoptotic mechanism of action on colon cancer cells. Initially, lethal concentrations (LC<sub>50</sub>...

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Bibliographic Details
Main Authors: Ulisses Moreno-Celis, F. Josué López-Martínez, Ricardo Cervantes-Jiménez, Roberto Augusto Ferríz-Martínez, Alejandro Blanco-Labra, Teresa García-Gasca
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
p53
Online Access:https://www.mdpi.com/1420-3049/25/5/1021