Isosorbide and nifedipine for Chagas' megaesophagus: A systematic review and meta-analysis.

BACKGROUND:Chagas disease is a neglected tropical disease. About 6 to 8 million people are chronically infected and 10% to 15% develop irreversible gastrointestinal disorders, including megaesophagus. Treatment focuses on improving symptoms, and isosorbide and nifedipine may be used for this purpose...

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Bibliographic Details
Main Authors: Celina Borges Migliavaca, Cinara Stein, Verônica Colpani, Sandro René Pinto de Sousa Miguel, Luciane Nascimento Cruz, Roberto Oliveira Dantas, Maicon Falavigna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6179300?pdf=render