More than just a gut feeling: constraint-based genome-scale metabolic models for predicting functions of human intestinal microbes

More than just a gut feeling: constraint-based genome-scale metabolic models for predicting functions of human intestinal microbes

Abstract The human gut is colonized with a myriad of microbes, with substantial interpersonal variation. This complex ecosystem is an integral part of the gastrointestinal tract and plays a major role in the maintenance of homeostasis. Its dysfunction has been correlated to a wide array of diseases,...

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Bibliographic Details
Main Authors: Kees C. H. van der Ark, Ruben G. A. van Heck, Vitor A. P. Martins Dos Santos, Clara Belzer, Willem M. de Vos
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Microbiome
Subjects:
Microbiome
Microbiota
Genome-scale metabolic model
Culturing
Minimal media
Phenotype prediction
Online Access:http://link.springer.com/article/10.1186/s40168-017-0299-x

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http://link.springer.com/article/10.1186/s40168-017-0299-x

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