New In Vitro Coculture Model for Evaluating Intestinal Absorption of Different Lipid Nanocapsules

New In Vitro Coculture Model for Evaluating Intestinal Absorption of Different Lipid Nanocapsules

Standard models used for evaluating the absorption of nanoparticles like Caco-2 ignore the presence of vascular endothelium, which is a part of the intestinal multi-layered barrier structure. Therefore, a coculture between the Caco-2 epithelium and HMEC-1 (Human Microvascular Endothelial Cell type 1...

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Bibliographic Details
Main Authors: Norraseth Kaeokhamloed, Emillie Roger, Jérôme Béjaud, Nolwenn Lautram, Florence Manero, Rodolphe Perrot, Chadi Abbara, Marie Briet, Samuel Legeay
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
intestinal absorption
Caco-2
HMEC-1
apparent permeability
lipid nanocapsule
förster resonance energy transfer
Online Access:https://www.mdpi.com/1999-4923/13/5/595

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https://www.mdpi.com/1999-4923/13/5/595

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