Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells

Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells

Abstract Background Mast cells (MCs) have been found to play a critical role during development of inflammatory bowel disease (IBD) that characterized by dysregulation of inflammation and impaired intestinal barrier function. However, the function of MCs in IBD remains to be fully elucidated. Result...

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Bibliographic Details
Main Authors: Musheng Li, Junhong Zhao, Meiwan Cao, Ruitao Liu, Guanhua Chen, Songyu Li, Yuanwen Xie, Jing Xie, Yang Cheng, Ling Huang, Mingmin Su, Yuxin Xu, Mingyue Zheng, Kejian Zou, Lanlan Geng, Wanfu Xu, Sitang Gong
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Biological Research
Subjects:
Mast cells
Exosomes
miR-223
Claudin 8
Inflammatory bowel disease
Online Access:http://link.springer.com/article/10.1186/s40659-020-00279-2

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http://link.springer.com/article/10.1186/s40659-020-00279-2

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