Non-isothermal stability by linear heating: a fast method for preformulation stability screening of drugs at the discovery and development interface

Abstract The non-isothermal method for prediction of chemical stability of pharmaceuticals has been discussed in the literature for almost half a century but it has not yet been systematically evaluated. The purpose of this study was to carry out a comprehensive experimental evaluation of the non-is...

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Bibliographic Details
Main Authors: Agnes Kairer, Shaoxin Feng, Valentino J. Stella, Thomas K. Karami
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:AAPS Open
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41120-017-0012-y