Amelioration of acute kidney injury in lipopolysaccharide-induced systemic inflammatory response syndrome by an aldose reductase inhibitor, fidarestat.

<h4>Background</h4>Systemic inflammatory response syndrome is a fatal disease because of multiple organ failure. Acute kidney injury is a serious complication of systemic inflammatory response syndrome and its genesis is still unclear posing a difficulty for an effective treatment. Aldos...

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Bibliographic Details
Main Authors: Kazunori Takahashi, Hiroki Mizukami, Kosuke Kamata, Wataru Inaba, Noriaki Kato, Chihiro Hibi, Soroku Yagihashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22253906/?tool=EBI