(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distributionResearch in context

(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distributionResearch in context

Background: In brain, CREB-regulated transcription co-activator 1 (CRTC1) is involved in metabolic dysregulation. In humans a SNP in CRTC1 was associated to body fat percentage and two SNPs affected RNA Pol II binding and chromatin structure, implying epigenetic regulation of CRTC1. We sought to und...

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Bibliographic Details
Main Authors: Kerstin Rohde, Maria Keller, Lars la Cour Poulsen, Torunn Rønningen, Michael Stumvoll, Anke Tönjes, Peter Kovacs, Annette Horstmann, Arno Villringer, Matthias Blüher, Yvonne Böttcher
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419303585

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http://www.sciencedirect.com/science/article/pii/S2352396419303585

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